What is GHD?
Growth hormone deficiency (GHD) occurs when the pituitary gland does not produce enough growth hormone to support normal linear growth. Children with GHD often have a reduced growth velocity over time rather than a single low measurement.
Typical signs
- Slow growth velocity: Height increases less than expected year‑to‑year for age.
- Younger appearance: Child may look younger than classmates with delayed dentition or delayed puberty later on.
- Other clues: Low IGF‑1/IGFBP‑3 on screening, history of pituitary issues, or symptoms like headaches or vision changes that need urgent care.
How GHD is evaluated
Evaluation begins with accurate serial measurements, growth velocity, and family height patterns. Screening labs can include IGF‑1 and IGFBP‑3, thyroid function, celiac screening, and others as indicated. A bone age X‑ray helps assess maturation. In some cases, formal growth hormone stimulation testing is performed, and an MRI may be considered when clinically indicated.
Treatment options
If a specialist diagnoses GHD, treatment may include recombinant human growth hormone with individualized dosing and monitoring. Families receive education on administration, expected responses, and follow‑up schedules. Response varies; the goal is to restore growth velocity while monitoring safety and overall health.
Internal link idea: Book a Growth Evaluation • FAQs on GHD • Parent Stories.
Quick FAQs
Is every slow grower GH‑deficient? No. Many children have normal variants like familial short stature or constitutional delay.
How quickly does treatment work? Clinicians track height every few months; early velocity changes guide ongoing care.
